4.4 Article

Metal-Free Arylalkylation of N-Aryl Acrylamides with Azobisalkyl-nitriles

期刊

SYNLETT
卷 26, 期 5, 页码 681-687

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1379888

关键词

metal-free; aryalkylation; acrylamide; AIBN; oxindole

资金

  1. National Natural Science Foundation of China [21272174]
  2. Key Projects of Shanghai in Biomedicine [08431902700]

向作者/读者索取更多资源

A novel metal-free arylalkylation of N-aryl acrylamides with readily available azobisalkylnitriles leading to cyano-containing oxindoles has been developed. The use of readily available azobisalkylnitriles and DTBP as oxidant makes this protocol environmentally benign and practical.

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