期刊
NUCLEIC ACIDS RESEARCH
卷 41, 期 D1, 页码 D738-D743出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gks1124
关键词
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资金
- Centre for BioSystems Genomics (CBSG) part of the Netherlands Genomics Initiative of the Netherlands Organisation for Scientific Research (NWO)
- Netherlands Consortium of Systems Biology (NCSB) part of the Netherlands Genomics Initiative of the Netherlands Organisation for Scientific Research (NWO)
- European Community [222936]
- ERASysbio-plus ZonMW project GRAPPLE [90201066]
- EU 7th Framework Programme under the Research Project PANACEA [222936]
Here, we present WormQTL (http://www.wormqtl.org), an easily accessible database enabling search, comparative analysis and meta-analysis of all data on variation in Caenorhabditis spp. Over the past decade, Caenorhabditis elegans has become instrumental for molecular quantitative genetics and the systems biology of natural variation. These efforts have resulted in a valuable amount of phenotypic, high-throughput molecular and genotypic data across different developmental worm stages and environments in hundreds of C. elegans strains. WormQTL provides a workbench of analysis tools for genotype-phenotype linkage and association mapping based on but not limited to R/qtl (http://www.rqtl.org). All data can be uploaded and downloaded using simple delimited text or Excel formats and are accessible via a public web user interface for biologists and R statistic and web service interfaces for bioinformaticians, based on open source MOLGENIS and xQTL workbench software. WormQTL welcomes data submissions from other worm researchers.
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