4.8 Article

959 Nematode Genomes: a semantic wiki for coordinating sequencing projects

期刊

NUCLEIC ACIDS RESEARCH
卷 40, 期 D1, 页码 D1295-D1300

出版社

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkr826

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资金

  1. School of Biological Sciences at the University of Edinburgh
  2. Natural Environment Research Council (NERC)
  3. Medical Research Council [G0900740] Funding Source: researchfish
  4. MRC [G0900740] Funding Source: UKRI

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Genome sequencing has been democratized by second-generation technologies, and even small labs can sequence metazoan genomes now. In this article, we describe '959 Nematode Genomes'-a community-curated semantic wiki to coordinate the sequencing efforts of individual labs to collectively sequence 959 genomes spanning the phylum Nematoda. The main goal of the wiki is to track sequencing projects that have been proposed, are in progress, or have been completed. Wiki pages for species and strains are linked to pages for people and organizations, using machine- and human-readable metadata that users can query to see the status of their favourite worm. The site is based on the same platform that runs Wikipedia, with semantic extensions that allow the underlying taxonomy and data storage models to be maintained and updated with ease compared with a conventional database-driven web site. The wiki also provides a way to track and share preliminary data if those data are not polished enough to be submitted to the official sequence repositories. In just over a year, this wiki has already fostered new international collaborations and attracted newcomers to the enthusiastic community of nematode genomicists. www.nematodegenomes.org.

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