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Loss of Repression of HuR Translation by miR-16 May Be Responsible for the Elevation of HuR in Human Breast Carcinoma
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Pre-mRNA Processing Reaches Back to Transcription and Ahead to Translation
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Ubiquitin-mediated proteolysis of HuR by heat shock
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HuR recruits let-7/RISC to repress c-Myc expression
Hyeon Ho Kim et al.
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The ELAV Protein HuD Stimulates Cap-Dependent Translation in a Poly(A)- and eIF4A-Dependent Manner
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The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis
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MicroRNA-125a represses cell growth by targeting HuR in breast cancer
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Cytoplasmic Expression of HuR is Related to Cyclooxygenase-2 Expression in Colon Cancer
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Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells
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Diverse molecular functions of Hu proteins
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Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
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miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels
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Protein factors in pre-mRNA 3'-end processing
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Prognostic role of HuR in hereditary breast cancer
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Analysis of turnover and translation regulatory RNA-Binding protein expression through binding to cognate mRNAs
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MOLECULAR AND CELLULAR BIOLOGY (2007)
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MOLECULAR CELL (2007)
Specific protein domains mediate cooperative assembly of HuR oligomers on AU-rich mRNA-destabilizing sequences
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
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NATURE REVIEWS GENETICS (2007)
Hu proteins regulate polyadenylation by blocking sites containing U-rich sequences
Hui Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators
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MOLECULAR BIOLOGY OF THE CELL (2006)
Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2
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Relief of microRNA-mediated translational repression in human cells subjected to stress
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CELL (2006)
Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR
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CLINICAL CANCER RESEARCH (2005)
Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma
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GYNECOLOGIC ONCOLOGY (2005)
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SCIENCE (2005)
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
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GENOME RESEARCH (2005)
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain -: art. no. 14
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BMC DEVELOPMENTAL BIOLOGY (2005)
Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR
R Pullmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma
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CANCER RESEARCH (2005)
The ELAV RNA-stability factor HuR binds the 5 '-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation
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NUCLEIC ACIDS RESEARCH (2005)
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Shared RNA-binding sites for interacting members of the Drosophila ELAV family of neuronal proteins
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Identification of a target RNA motif for RNA-binding protein HuR
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Transcriptional control of SV40 T-antigen expression allows a complete reversion of immortalization
T May et al.
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Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression
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ELAV inhibits 3′-end processing to promote neural splicing of ewg pre-mRNA
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GENES & DEVELOPMENT (2003)
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation
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Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR
I Yaman et al.
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Complex formation of the neuron-specific ELAV-like hu RNA-binding proteins
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Eukaryotic mRNPs may represent posttranscriptional operons
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MOLECULAR CELL (2002)
AMP-activated kinase regulates cytoplasmic HuR
W Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA
MJ Lisbin et al.
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Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence
WG Wang et al.
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CELLULAR AND MOLECULAR LIFE SCIENCES (2001)
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HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation
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HuR binding to cytoplasmic mRNA is perturbed by heat shock
IE Gallouzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
HuR regulates p21 mRNA stabilization by UV light
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MOLECULAR AND CELLULAR BIOLOGY (2000)