期刊
NUCLEIC ACIDS RESEARCH
卷 40, 期 D1, 页码 D1093-D1099出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkr1177
关键词
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资金
- National Science Foundation (DBI) [0544757]
- National Institutes of Health (NIGMS) [5R01 GM076680-02]
- National Institutes of Health (NIDDK) [UO1 DK072473, 1U01DK089571-01]
- McMillen Foundation
- Seattle Children's
- Div Of Biological Infrastructure [0969929] Funding Source: National Science Foundation
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [U01DK072473, U01DK089571] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM076680] Funding Source: NIH RePORTER
Large numbers of mass spectrometry proteomics studies are being conducted to understand all types of biological processes. The size and complexity of proteomics data hinders efforts to easily share, integrate, query and compare the studies. The Model Organism Protein Expression Database (MOPED, htttp://moped.proteinspire.org) is a new and expanding proteomics resource that enables rapid browsing of protein expression information from publicly available studies on humans and model organisms. MOPED is designed to simplify the comparison and sharing of proteomics data for the greater research community. MOPED uniquely provides protein level expression data, meta-analysis capabilities and quantitative data from standardized analysis. Data can be queried for specific proteins, browsed based on organism, tissue, localization and condition and sorted by false discovery rate and expression. MOPED empowers users to visualize their own expression data and compare it with existing studies. Further, MOPED links to various protein and pathway databases, including GeneCards, Entrez, UniProt, KEGG and Reactome. The current version of MOPED contains over 43 000 proteins with at least one spectral match and more than 11 million high certainty spectra.
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