4.8 Article

mirEX: a platform for comparative exploration of plant pri-miRNA expression data

期刊

NUCLEIC ACIDS RESEARCH
卷 40, 期 D1, 页码 D191-D197

出版社

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkr878

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资金

  1. Polish Ministry of Science and Higher Education [3011/B/P01/2009/37]
  2. Faculty of Biology Adam Mickiewicz University in Poznan, Poland
  3. Foundation for Polish Science (FNP)
  4. European Union [MPD 2010/3]
  5. Faculty of Biology Adam Mickiewicz University

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mirEX is a comprehensive platform for comparative analysis of primary microRNA expression data. RT-qPCR-based gene expression profiles are stored in a universal and expandable database scheme and wrapped by an intuitive user-friendly interface. A new way of accessing gene expression data in mirEX includes a simple mouse operated querying system and dynamic graphs for data mining analyses. In contrast to other publicly available databases, the mirEX interface allows a simultaneous comparison of expression levels between various microRNA genes in diverse organs and developmental stages. Currently, mirEX integrates information about the expression profile of 190 Arabidopsis thaliana pri-miRNAs in seven different developmental stages: seeds, seedlings and various organs of mature plants. Additionally, by providing RNA structural models, publicly available deep sequencing results, experimental procedure details and careful selection of auxiliary data in the form of web links, mirEX can function as a one-stop solution for Arabidopsis microRNA information. A web-based mirEX interface can be accessed at http://bioinfo.amu.edu.pl/mirex.

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