期刊
NUCLEIC ACIDS RESEARCH
卷 39, 期 -, 页码 D1171-D1176出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkq998
关键词
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资金
- Histogenetics
- Abbott Molecular Laboratories Inc.
- Bio-Rad
- Gen-Probe, Invitrogen by Life Technologies
- European Federation for Immunogenetics
- Innogenetics
- One Lambda Inc.
- Olersup SSP
- American Society for Histocompatibility and Immunogenetics
- Anthony Nolan
- BAG Healthcare
- Be the Match Foundation
- Marrow Foundation
- National Marrow Donor Program
- Rose and Zentrum Knochenmarkspender-Register Deutschland
- Imperial Cancer Research Fund
- EU [BIO4CT960037]
It is 12 years since the IMGT/HLA database was first released, providing the HLA community with a searchable repository of highly curated HLA sequences. The HLA complex is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse function. Many of the genes encode proteins of the immune system and are highly polymorphic. The naming of these HLA genes and alleles and their quality control is the responsibility of the WHO Nomenclature Committee for Factors of the HLA System. Through the work of the HLA Informatics Group and in collaboration with the European Bioinformatics Institute, we are able to provide public access to this data through the web site http://www.ebi.ac.uk/imgt/hla/. Regular updates to the web site ensure that new and confirmatory sequences are dispersed to the HLA community, and the wider research and clinical communities.
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