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DNA damage and radical reactions: Mechanistic aspects, formation in cells and repair studies
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Processing of DNA damage clusters in human cells: current status of knowledge
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Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency
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Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences
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A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol
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Closely opposed apurinic/apyrimidinic sites are converted to double strand breaks in Escherichia coli even in the absence of exonuclease III, endonuclease IV, nucleotide excision repair and AP lyase cleavage
L Harrison et al.
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The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage
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Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions
A Katafuchi et al.
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8-oxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site
ME Lomax et al.
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Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation
M Gulston et al.
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Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts
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Are endogenous clustered DNA damages induced in human cells?
PV Bennett et al.
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Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage site
CG Pearson et al.
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Two clustered 8-oxo-7,8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli
S Malyarchuk et al.
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Stereoselective excision of thymine glycol from oxidatively damaged DNA
H Miller et al.
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Low levels of endogenous oxidative damage cluster levels in unirradiated viral and human DNAs
BM Sutherland et al.
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Repair of clustered uracil DNA damages in Escherichia coli
DI D'souza et al.
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The mutation frequency of 8-oxo-7,8-dihydroguanine (8-oxodG) situated in a multiply damaged site:: comparison of a single and two closely opposed 8-oxodG in Escherichia coli
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Mode of inhibition of short-patch base excision repair by thymine glycol within clustered DNA lesions
H Budworth et al.
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Clustered DNA damage induced by radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites
M Gulston et al.
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Biological consequences of free radical-damaged DNA bases
SS Wallace
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Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease
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Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein
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Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
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High-performance liquid chromatography-tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA
S Frelon et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2000)
Single nucleotide patch base excision repair is the major pathway for removal of thymine glycol from DNA in human cell extracts
GL Dianov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
BM Sutherland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)