期刊
NUCLEIC ACIDS RESEARCH
卷 38, 期 -, 页码 D570-D576出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkp799
关键词
-
资金
- European Commission [506455]
- Medical Research Council [MC_U142684171, MC_UP_1502/1, MC_U142684172, MC_U142684175] Funding Source: researchfish
- MRC [MC_U142684172, MC_U142684175, MC_UP_1502/1, MC_U142684171] Funding Source: UKRI
The laboratory mouse is the premier animal model for studying human disease and thousands of mutants have been identified or produced, most recently through gene-specific mutagenesis approaches. High throughput strategies by the International Knockout Mouse Consortium (IKMC) are producing mutants for all protein coding genes. Generating a knock-out line involves huge monetary and time costs so capture of both the data describing each mutant alongside archiving of the line for distribution to future researchers is critical. The European Mouse Mutant Archive (EMMA) is a leading international network infrastructure for archiving and worldwide provision of mouse mutant strains. It operates in collaboration with the other members of the Federation of International Mouse Resources (FIMRe), EMMA being the European component. Additionally EMMA is one of four repositories involved in the IKMC, and therefore the current figure of 1700 archived lines will rise markedly. The EMMA database gathers and curates extensive data on each line and presents it through a user-friendly website. A BioMart interface allows advanced searching including integrated querying with other resources e. g. Ensembl. Other resources are able to display EMMA data by accessing our Distributed Annotation System server. EMMA database access is publicly available at http://www.emmanet.org.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据