期刊
NUCLEIC ACIDS RESEARCH
卷 38, 期 -, 页码 D443-D447出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkp910
关键词
-
资金
- National Human Genome Research Institute at the US NIH [P41 HG000739]
- EPSRC MPhil studentship
- Medical Research Council
- Royal Society
- NATIONAL HUMAN GENOME RESEARCH INSTITUTE [P41HG000739] Funding Source: NIH RePORTER
- Medical Research Council [MC_U105161047, G0500293] Funding Source: researchfish
- MRC [MC_U105161047, G0500293] Funding Source: UKRI
FlyTF (http://www.flytf.org) is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. The manual classification of TFs in the initial version of FlyTF that concentrated primarily on the DNA-binding characteristics of the proteins has now been extended to a more fine-grained annotation of both DNA binding and regulatory properties in the new release. Furthermore, experimental evidence from the literature was classified into a defined vocabulary, and in collaboration with FlyBase, translated into Gene Ontology (GO) annotation. While our GO annotations will also be available through FlyBase as they will be incorporated into the genes' official GO annotation in the future, the entire evidence used for classification including computational predictions and quotes from the literature can be accessed through FlyTF. The FlyTF website now builds upon the InterMine framework, which provides experimental and computational biologists with powerful search and filter functionality, list management tools and access to genomic information associated with the TFs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据