期刊
NUCLEAR MEDICINE AND BIOLOGY
卷 37, 期 1, 页码 51-55出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nucmedbio.2009.08.007
关键词
Fluoro-2-deoxy-D-glucose; Chemoresistance; PET; p53
Both mutant p53 and chemoresistance are poor prognostic factors in cancer. Many studies have examined the influence of these factors on fluoro-2-deoxy-D-glucose (FDG) incorporation. Whilst mutant p53 is associated with increased FDG incorporation, chemoresistance, especially when associated with P-glycoprotein, is associated with decreased FDG incorporation. (C) 2010 Elsevier Inc. All rights reserved.
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