期刊
NEW PHYTOLOGIST
卷 221, 期 3, 页码 1253-1259出版社
WILEY
DOI: 10.1111/nph.15434
关键词
complex traits; DNA methylation; epigenetic inheritance; genome evolution; plant epigenetics; plant evolution
资金
- Technical University of Munich-Institute for Advanced Study - German Excellent Initiative
- European Seventh Framework Programme [291763]
- Deutsche Forschungsgemeinschaft (DFG) [SFB/Sonderforschungsbereich924]
- National Science Foundation [IOS-1546867]
- Pew Charitable Trusts
Heritable gains or losses of cytosine methylation can arise stochastically in plant genomes independently of DNA sequence changes. These so-called 'spontaneous epimutations' appear to be a byproduct of imperfect DNA methylation maintenance and epigenome reinforcement events that occur in specialized cell types. There is continued interest in the plant epigenetics community in trying to understand the broader implications of these stochastic events, as some have been shown to induce heritable gene expression changes, shape patterns of methylation diversity within and among plant populations, and appear to be responsive to multi-generational environmental stressors. In this paper we synthesized our current knowledge of the molecular basis and functional consequences of spontaneous epimutations in plants, discuss technical and conceptual challenges, and highlight emerging research directions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据