期刊
NEW ENGLAND JOURNAL OF MEDICINE
卷 365, 期 1, 页码 62-70出版社
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMcp1012926
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资金
- VA [873765, 5I01BX000436-07] Funding Source: Federal RePORTER
- BLRD VA [I01 BX000436] Funding Source: Medline
A 55-year-old woman with severe, persistent asthma requiring glucocorticoid therapy for the past 3 months presents for care. Her medications include albuterol, inhaled fluticasone with salmeterol, montelukast, and prednisone (at a dose of 10 mg per day). In the past, she received several intermittent courses of prednisone at a dose of 15 mg or more per day. Her weight is 45.5 kg (100 lb), and her height 157.5 cm (62 in.); the body-mass index (the weight in kilograms divided by the square of the height in meters) is 18. Scattered wheezing is heard during expiration. Findings on vertebral percussion and rib-cage compression are unremarkable. How should her case be evaluated and managed to minimize the risk of fractures?
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