期刊
NEW ENGLAND JOURNAL OF MEDICINE
卷 360, 期 11, 页码 1096-1101出版社
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMoa0803645
关键词
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资金
- Alliance for Paired Donation
- Life Connection of Ohio
- University of Toledo
- Charles T. Bauer Foundation
- National Science Foundation
- Sloan Foundation Fellowship
- Novartis
- Bristol-Myers Squibb, Wyeth
- Novartis
- Dr. Pankewycz
- Novartis, Astellas
- Genzyme and consulting fees from Genzyme and Astellas
We report a chain of 10 kidney transplantations, initiated in July 2007 by a single altruistic donor (i.e., a donor without a designated recipient) and coordinated over a period of 8 months by two large paired-donation registries. These transplantations involved six transplantation centers in five states. In the case of five of the transplantations, the donors and their coregistered recipients underwent surgery simultaneously. In the other five cases, ``bridge donors'' continued the chain as many as 5 months after the coregistered recipients in their own pairs had received transplants. This report of a chain of paired kidney donations, in which the transplantations were not necessarily performed simultaneously, illustrates the potential of this strategy.
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