期刊
NEW BIOTECHNOLOGY
卷 28, 期 2, 页码 97-109出版社
ELSEVIER
DOI: 10.1016/j.nbt.2010.09.011
关键词
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资金
- Alberta Crop Industry
- Natural Sciences and Engineering Research Council of Canada
- Canada Research Chairs Program
Acyl-CoA-binding protein (ACBP), a low molecular mass (m) (similar to 10 kDa) soluble protein ubiquitous in eukaryotes, plays an important housekeeping role in lipid metabolism by maintaining the intracellular acyl-CoA pool. ACBP is involved in lipid biosynthesis and transport, gene expression, and membrane biogenesis. In plants, low m ACBP and high m ACBPs participate in response mechanisms to biotic and abiotic factors, acyl-CoA transport in phloem, and biosynthesis of structural and storage lipids. In light of current research on the modification of seed oil, insight into mechanisms of substrate trafficking within lipid biosynthetic pathways is crucial for developing rational strategies for the production of specialty oils with the desired alterations in fatty acid composition. In this review, we summarize our knowledge of plant ACBPs with emphasis on the role of low m ACBP in seed oil biosynthesis, based on in vitro studies and analyses of transgenic plants. Future prospects and possible applications of low m ACBP in seed oil modification are discussed.
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