期刊
NEUROTHERAPEUTICS
卷 7, 期 4, 页码 338-353出版社
SPRINGER
DOI: 10.1016/j.nurt.2010.07.006
关键词
Astrocytes; potassium buffering; pH control; receptors; transmitter uptake; blood flow; aquaporins; lactate shuttle; antioxidant; Muller cells; ensheathment
资金
- U.S. National Institutes of Health [NS50350]
- Leila Y. and G. Harold Mathers Charitable Foundation
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P01NS050315] Funding Source: NIH RePORTER
Astrocytes are often referred to, and historically have been regarded as, support cells of the mammalian CNS. Work over the last decade suggests otherwise-that astrocytes may in fact play a more active role in higher neural processing than previously recognized. Because astrocytes can potentially serve as novel therapeutic targets, it is critical to understand how astrocytes execute their diverse supportive tasks while maintaining neuronal health. To that end, this review focuses on the supportive roles of astrocytes, a line of study relevant to essentially all acute and chronic neurological diseases, and critically re-evaluates our concepts of the functional properties of astrocytes and relates these functions and properties to the intricate morphology of these cells.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据