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Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis
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Olivier L. Chinot et al.
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Richard J. Shaw et al.
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Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas
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MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
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Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors
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T Kamiryo et al.
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