期刊
NEUROSCIENCE LETTERS
卷 457, 期 2, 页码 107-110出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neulet.2009.03.090
关键词
Major depression; Moral emotions; Individual differences; Subgenual cingulate cortex; Social cognition; Empathy
资金
- LABS D'Or Hospital Network
- PHONEX-CNPq
- University of Manchester
- FASEP [03/11794-6]
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [03/11794-6] Funding Source: FAPESP
Recent fMRI studies linked subgenual cingulate cortex (SCC) activity with feelings of guilt for acting counter to social values and altruistic donations towards societal causes. We hypothesized that SCC activity across those different tasks was driven by feelings of attachment. In order to investigate this further, we used fMRI to probe the association of empathic concern and strength of SCC activation in response to guilt- and compassion-evoking verbal descriptions of social behaviour. We were able to confirm our prediction that participants with higher empathic concern had increased activity in the SCC in the guilt condition, whereas there was no association for compassion. These results shed new light on the role of the SCC which shows abnormalities in clinical depression. Crown Copyright (C) 2009 Published by Elsevier Ireland Ltd. All rights reserved.
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