期刊
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
卷 37, 期 9, 页码 2087-2091出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2013.09.011
关键词
Psychosis; Psychopharmacology; Behavior; Rat; Mouse; Non-human primate
资金
- NIMH NIH HHS [1R13MH078710, R13 MH078710, P50 MH086404] Funding Source: Medline
- NINDS NIH HHS [P01 NS048120] Funding Source: Medline
Over the past two decades, the awareness of the disabling and treatment-refractory effects of impaired cognition in schizophrenia has increased dramatically. In response to this still unmet need in the treatment of schizophrenia, the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative was developed. The goal of CNTRICS is to harness cognitive neuroscience to develop a brain-based set of tools for measuring cognition in schizophrenia and to test new treatments. CNTRICS meetings focused on development of tasks with cognitive construct validity for use in both human and animal model studies. This special issue presents papers discussing the cognitive testing paradigms selected by CNTRICS for animal model systems. These paradigms are designed to measure cognitive constructs within the domains of perception, attention, executive function, working memory, object/relational long-term memory, and social/affective processes. (C) 2013 Elsevier Ltd. All rights reserved.
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