期刊
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
卷 37, 期 3, 页码 358-373出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2013.01.001
关键词
Action tendencies; Appraisal; Arousal; Basal ganglia; Deep brain stimulation; Dopamine; Emotion; Emotional prosody; Faces; fMRI; Intracranial recordings; Obsessive-compulsive disorder; Parkinson's disease; PET; Recognition; Relevance; Subjective feeling; Subthalamic nucleus; Theory of mind
资金
- National Center of Competence in Research (NCCR)
- Swiss National Science Foundation [51NF40-104897]
Affective neuroscience is concerned with identifying the neural bases of emotion. For historical and methodological reasons, models describing the brain architecture that supports emotional processes in humans have tended to neglect the basal ganglia, focusing instead on cortical and amygdalar mechanisms. Now, however, deep brain stimulation (DBS) of the subthalamic nucleus (STN), a neurosurgical treatment for Parkinson's disease and obsessive-compulsive disorder, is helping researchers explore the possible functional role of this particular basal ganglion in emotional processes. After reviewing studies that have used DBS in this way, we propose a model in which the STN plays a crucial role in producing temporally organized neural co-activation patterns at the cortical and subcortical levels that are essential for generating emotions and related feelings. (C) 2013 Elsevier Ltd. All rights reserved.
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