期刊
NEUROREPORT
卷 20, 期 11, 页码 984-989出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/WNR.0b013e32832d0a67
关键词
anxiety; functional magnetic resonance imaging; mentalizing; social cognition; trust
资金
- National Institute of Mental Health (NIMH) [MH076198]
- Brain Research Foundation
- NIMH Mental Health Research Education [R25MH063742]
- University of Chicago, Chicago, Illinois, USA
Individuals with generalized social anxiety disorder tend to make overly negative and distorted predictions about social events, which enhance perceptions of threat and contribute to excessive anxiety in social situations. Here, we coupled functional magnetic resonance imaging and a multiround economic exchange game ('trust game') to probe mentalizing, the social-cognitive ability to attribute mental states to others. Relative to interactions with a computer, those with human partners ('mentalizing') elicited less activation of medial prefrontal cortex in generalized social anxiety patients compared with matched healthy control participants. Diminished medial prefrontal cortex function may play a role in the social-cognitive pathophysiology of social anxiety. NeuroReport 20:984-989 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据