期刊
NEUROREPORT
卷 19, 期 7, 页码 703-709出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/WNR.0b013e3282fb8203
关键词
commissurotomy; diffusion tensor imaging; interhemispheric interaction; laterality; resting-state functional connectivity
资金
- NIMH NIH HHS [5R21MH066393, 5T32MH067763, T32 MH067763, R21 MH066393] Funding Source: Medline
- NINDS NIH HHS [NS20187, R01 NS020187] Funding Source: Medline
Split-brain patients present a unique opportunity to address controversies regarding subcortical contributions to interhemispheric coordination. We characterized residual functional connectivity in a complete commissurotomy patient by examining patterns of low-frequency BOLD functional MRI signal. Using independent components analysis and region-of-interest-based functional connectivity analyses, we demonstrate bilateral resting state networks in a patient lacking all major cerebral commissures. Compared with a control group, the patient's interhemispheric correlation scores fell within the normal range for two out of three regions examined. Thus, we provide evidence for bilateral resting state networks in a patient with complete commissurotomy. Such continued interhemispheric interaction suggests that, at least in part, cortical networks in the brain can be coordinated by subcortical mechanisms.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据