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J. P. Robinson et al.
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Oren J. Becher et al.
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J. P. Robinson et al.
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Lauren T. McGillicuddy et al.
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Yuan Wang et al.
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Nanna Lindberg et al.
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An Claes et al.
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Aiguo Li et al.
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L. Chin et al.
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Dominique B. Hoelzinger et al.
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Girish C. Daginakatte et al.
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Henry M. Smilowitz et al.
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HS Phillips et al.
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AH Shih et al.
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P Shannon et al.
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Y Zhu et al.
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A Xiao et al.
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JN Rich et al.
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C Giannini et al.
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R Galli et al.
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Andrew B. Lassman et al.
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LCLT van Kempen et al.
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ML Bajenaru et al.
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