期刊
NEURON
卷 83, 期 3, 页码 518-532出版社
CELL PRESS
DOI: 10.1016/j.neuron.2014.07.016
关键词
-
资金
- NIH [R01 NS045193, F31 MH098651]
- Nancy Lurie Marks Family Foundation
- Sutherland Cook Fund
Cerebellar research has focused principally on adult motor function. However, the cerebellum also maintains abundant connections with nonmotor brain regions throughout postnatal life. Here we review evidence that the cerebellum may guide the maturation of remote nonmotor neural circuitry and influence cognitive development, with a focus on its relationship with autism. Specific cerebellar zones influence neocortical substrates for social interaction, and we propose that sensitive-period disruption of such internal brain communication can account for autism's key features.
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