期刊
NEURON
卷 80, 期 3, 页码 648-657出版社
CELL PRESS
DOI: 10.1016/j.neuron.2013.10.036
关键词
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资金
- Wellcome Trust
- European Research Council
- Max Planck Society
- DFG [CRC 902, 1080]
- DFG (Cluster of Excellence for Macromolecular Complexes, Goethe University)
The elaborate morphology of neurons together with the information processing that occurs in remote dendritic and axonal compartments makes the use of decentralized cell biological machines necessary. Recent years have witnessed a revolution in our understanding of signaling in neuronal compartments and the manifold functions of a variety of RNA molecules that regulate protein translation and other cellular functions. Here we discuss the view that mRNA localization and RNA-regulated and localized translation underlie many fundamental neuronal processes and highlight key issues for future experiments.
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