期刊
NEURON
卷 75, 期 2, 页码 194-208出版社
CELL PRESS
DOI: 10.1016/j.neuron.2012.06.011
关键词
-
资金
- NIH [R01 EY04726, R01 EY019288]
- Pew Charitable Trusts
Orientation selectivity in the primary visual cortex (VI) is a receptive field property that is at once simple enough to make it amenable to experimental and theoretical approaches and yet complex enough to represent a significant transformation in the representation of the visual image. As a result, V1 has become an area of choice for studying cortical computation and its underlying mechanisms. Here we consider the receptive field properties of the simple cells in cat V1-the cells that receive direct input from thalamic relay cells and explore how these properties, many of which are highly nonlinear, arise. We have found that many receptive field properties of V1 simple cells fall directly out of Hubei and Wiesel's feedforward model when the model incorporates realistic neuronal and synaptic mechanisms, including threshold, synaptic depression, response variability, and the membrane time constant.
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