期刊
NEURON
卷 71, 期 4, 页码 737-749出版社
CELL PRESS
DOI: 10.1016/j.neuron.2011.07.012
关键词
-
资金
- NIMH [MH71702, MH095297]
- Division Of Mathematical Sciences
- Direct For Mathematical & Physical Scien [1042134] Funding Source: National Science Foundation
The hippocampus is critical to remembering the flow of events in distinct experiences and, in doing so, bridges temporal gaps between discontiguous events. Here, we report a robust hippocampal representation of sequence memories, highlighted by time cells that encode successive moments during an empty temporal gap between the key events, while also encoding location and ongoing behavior. Furthermore, just as most place cells remap when a salient spatial cue is altered, most time cells form qualitatively different representations (retime) when the main temporal parameter is altered. Hippocampal neurons also differentially encode the key events and disambiguate different event sequences to compose unique, temporally organized representations of specific experiences. These findings suggest that hippocampal neural ensembles segment temporally organized memories much the same as they represent locations of important events in spatially defined environments.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据