4.8 Article

Multisensory Integration of Natural Odors and Sounds in the Auditory Cortex

期刊

NEURON
卷 72, 期 2, 页码 357-369

出版社

CELL PRESS
DOI: 10.1016/j.neuron.2011.08.019

关键词

-

资金

  1. Edmond and Lily Safra Center for Brain Sciences
  2. European Research Council [203994]
  3. European Research Council (ERC) [203994] Funding Source: European Research Council (ERC)

向作者/读者索取更多资源

Motherhood is associated with different forms of physiological alterations including transient hormonal changes and brain plasticity. The underlying impact of these changes on the emergence of maternal behaviors and sensory processing within the mother's brain are largely unknown. By using in vivo cell-attached recordings in the primary auditory cortex of female mice, we discovered that exposure to pups' body odor reshapes neuronal responses to pure tones and natural auditory stimuli. This olfactory-auditory interaction appeared naturally in lactating mothers shortly after parturition and was long lasting. Naive virgins that had experience with the pups also showed an appearance of olfactory-auditory integration in A1, suggesting that multisensory integration may be experience dependent. Neurons from lactating mothers were more sensitive to sounds as compared to those from experienced mice, independent of the odor effects. These uni- and multisensory cortical changes may facilitate the detection and discrimination of pup distress calls and strengthen the bond between mothers and their neonates.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据