期刊
NEUROMUSCULAR DISORDERS
卷 19, 期 12, 页码 818-821出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.nmd.2009.09.007
关键词
Charcot-Marie-Tooth disease; Foot; Ankle; Weakness; Strength; Therapy; Intervention; Child
资金
- The University of Sydney Research and Development Scheme [K2701 U3332]
- National Health and Medical Research Council of Australia [336705]
Weakness of ankle dorsiflexion is the cardinal manifestation of CMT. We investigated if a 12-week progressive resistance dorsiflexion strengthening program was feasible, safe and beneficial in a 15-year-old girl with an axonal form of CMT. Training load was based on a dose-escalating percentage of one-repetition maximum. completed on three non-consecutive days each week. Outcomes included dynamometric foot strength, motor function and instrumented walking ability. At 12-weeks, dorsiflexion strength improved 56-72% and plantarflexion strength by 15-20%. Standing long jump increased by 16%, while balance and endurance did not. Walking ability improved for speed, cadence, step time and stride length. Compliance was high and there were no adverse events. This case suggests progressive strength training might be a feasible intervention to help foot weakness and disability in childhood CMT. (C) 2009 Elsevier B.V. All rights reserved.
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