期刊
NEUROMOLECULAR MEDICINE
卷 10, 期 2, 页码 99-107出版社
HUMANA PRESS INC
DOI: 10.1007/s12017-008-8026-1
关键词
insulin-like growth factor 1; physical exercise; hippocamus-dependent learning; adult hippocampal neurogenesis; cognitive impairment
Physical exercise has long been recognized as highly beneficial for brain and body health. The molecular mechanisms responsible for translation of exercise stimuli in the brain have claimed attention due to mounting evidence for the neuroprotective actions of the exercise and its positive effects in preventing both ageing and neurodegenerative disease. These molecular mediators are currently under investigation with new tools able to yield deep insights into the neurobiology of exercise. In the present work we focus on the evidence pertaining to the mediation of exercise effects by insulin-like growth factor 1 (IGF1), as recent reports suggest that this growth factor shows brain area-specific, temporal rank-sensitive, and behavioural task-dependent features in response to exercise.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据