期刊
NEUROMODULATION
卷 17, 期 1, 页码 54-59出版社
WILEY
DOI: 10.1111/ner.12130
关键词
chronic pain; headache; migraine; neuromodulation; occipital nerve stimulation; outcome measure; peripheral nerve field stimulation
资金
- MetroSpinal Clinic, Caulfield South, Victoria, Australia
ObjectiveThe objective of this study is to evaluate the efficacy of peripheral nerve field stimulation (PNFS) for the treatment of chronic headache conditions. Materials and MethodsFor more than a four-year period, 83 patients underwent a trial of a PNFS system targeting the nerve regions including occipital and supraorbital and infraorbital nerves, which best corresponded with their area of head pain. Sixty patients reported a successful trial and underwent a subsequent implant of the PNFS system. Questionnaires, along with patients' charts, were used to assess outcomes as follows: pain (11-point numerical pain rating scale), analgesic use, depression (Zung Depression Scale), disability (Neck Disability Index), patient satisfaction, and surgical complications. Patients were followed up for an average of 12.9 9.4 months (range 3-42 months). ResultsAn average pain reduction of 4.8 +/- 2.3 pain scale points was observed (preimplant 7.4 +/- 1.6; follow-up 2.6 +/- 2.1 [p 0.001]). Of the 60 patients implanted, 41 reported >50% pain relief. Medication use was reduced in 83% of patients who were previously taking analgesics or prophylactic medications. Similarly, reductions in degree of disability and depression also were observed. Of the 60 cases, ten surgical revisions were required; however, no long-term complications were reported. ConclusionsPNFS for chronic headache is an evolving therapy. This study demonstrates that this reversible and effective treatment can be a promising pain relief strategy for this often intractable condition.
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