期刊
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
卷 135, 期 -, 页码 198-202出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2014.06.082
关键词
D-Penicillamine; Fluorescence; Gold nanoclusters; Cupric ion; Turn-on sensor
类别
资金
- National Natural Science Foundation of China [21273174, 20975083]
- Municipal Science Foundation of Chongqing City [CSTC-2013jjB00002]
In this contribution, a luminescent gold nanoclusters which were synthesized by bovine serum albumin as novel fluorescent probes were successfully utilized for the determination of D-penicillamine for the first time. Cupric ion was employed to quench the strong fluorescence of the gold nanoclusters, whereas the addition of D-penicillamine caused obvious restoration of fluorescence intensity of the Cu2+-gold nanoclusters system. Under optimum conditions, the increment in fluorescence intensity of Cu2+-gold nanoclusters system caused by D-penicillamine was linearly proportional to the concentration of D-penicillamine in the range of 2.0 x 10(-5)-2.39 x 10(-4) M. The detection limit for D-penicillamine was 5.4 x 10(-6) M. With the off-on fluorescence signal at 650 nm approaching the near-infrared region, the present sensor for D-penicillamine detection had high sensitivity and low spectral interference. Furthermore, the novel gold nanoclusters-based fluorescent sensor has been applied to the determination of D-penicillamine in real biological samples with satisfactory results. (C) 2014 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据