期刊
NEUROIMAGING CLINICS OF NORTH AMERICA
卷 21, 期 2, 页码 285-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nic.2011.01.003
关键词
Arterial spin labeling; Perfusion; Cerebral blood flow; Cerebrovascular disease; Stroke; Transient ischemic attack
资金
- NINDS NIH HHS [R01 NS066506, R01 NS066506-01, R01-NS066506-01] Funding Source: Medline
Since acute stroke and transient ischemic attack (TIA) are disruptions of brain hemodynamics, perfusion neuroimaging might be of clinical utility. Recently, arterial spin labeling (ASL), a noncontrast perfusion method, has become clinically feasible. It has advantages compared to contrast bolus perfusion-weighted imaging (PWI) including lack of exposure to gadolinium, improved quantitation, and decreased sensitivity to susceptibility and motion. Drawbacks include reduced signal-to-noise and high sensitivity to arterial transit delays. However, this sensitivity can enable visualization of collateral flow. This article discusses ASL findings in patients with acute stroke and TIA, focusing on typical appearances, common artifacts, and comparisons with PWI.
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