期刊
NEUROIMAGE
卷 99, 期 -, 页码 142-148出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2014.05.007
关键词
Human; Go/no-go task
资金
- MEXT/JSPS KAKENHI [19002010, 24220008]
- [22300134]
It has been demonstrated that motor learning is supported by the cerebellum and the cerebro-cerebellar interaction. Response inhibition involves motor responses and the higher-order inhibition that controls the motor responses. In this functional MRI study, we measured the cerebro-cerebellar interaction during response inhibition in two separate days of task performance, and detected the changes in the interaction following performance improvement Behaviorally, performance improved in the second day, compared to the first day. The psycho-physiological interaction (PP!) analysis revealed the interaction decrease from the right inferior frontal cortex (rIFC) to the cerebellum (lobule VII or VI). It was also revealed that the interaction increased from the same cerebellar region to the primary motor area. These results suggest the involvement of the cerebellum in response inhibition, and raise the possibility that the performance improvement was supported by the changes in the cerebro-cerebellar interaction. (C) 2014 Elsevier Inc All rights reserved.
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