期刊
NEUROIMAGE
卷 83, 期 -, 页码 991-1001出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2013.07.055
关键词
Blipped CAIPI; Leakage (L-) factor; g-Factor Residual aliasing; Spectral analysis; Single-shot fMRI time series
资金
- Human Connectome Project [U54MH091657-01]
- 16 National Institutes of Health (NIH) Institutes and Centers that support the NIH Blueprint for Neuroscience research
- National Center for Research Resources [P41 RR008079]
- National Institute of Biomedical Imaging and Bioengineering [P41 EB015894]
- NIH [R44 NS073417, P30 N5057091, P30 NS076408]
We evaluate residual aliasing among simultaneously excited and acquired slices in slice accelerated multiband (MB) echo planar imaging (EPI). No in-plane accelerations were used in order to maximize and evaluate achievable slice acceleration factors at 3 T. We propose a novel leakage (L-) factor to quantify the effects of signal leakage between simultaneously acquired slices. With a standard 32-channel receiver coil at 3 T, we demonstrate that slice acceleration factors of up to eight (MB = 8) with blipped controlled aliasing in parallel imaging (CAIPI), in the absence of in-plane accelerations, can be used routinely with acceptable image quality and integrity for whole brain imaging. Spectral analyses of single-shot fMRI time series demonstrate that temporal fluctuations due to both neuronal and physiological sources were distinguishable and comparable up to sliceacceleration factors of nine (MB = 9). The increased temporal efficiency could be employed to achieve, within a given acquisition period, higher spatial resolution, increased fMRI statistical power, multiple TEs, faster sampling of temporal events in a resting state fMRI time series, increased sampling of q-space in diffusion imaging, or more quiet time during a scan. (C) 2013 Elsevier Inc. All rights reserved.
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