期刊
NEUROIMAGE
卷 62, 期 2, 页码 1299-1310出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2012.01.032
关键词
Brain; Magnetic Resonance Imaging; MRI; Connectivity; Tractography; Functional imaging; fMRI; Resting state; Diffusion imaging; Multiband; Ultrahigh field imaging; 7 Tesla
资金
- 16 NIH Institutes and Centers [1U54MH091657-01]
- NIMH [R01 MH 60974]
- National Center for Research Resources (NCRR) [P41 RR008079]
The opportunity to explore the human connectome using cutting-edge neuroimaging methods has elicited widespread interest. How far will the field be able to progress in deciphering long-distance connectivity patterns and in relating differences in connectivity to phenotypic characteristics in health and disease? We discuss the daunting nature of this challenge in relation to specific complexities of brain circuitry and known limitations of in vivo imaging methods. We also discuss the excellent prospects for continuing improvements in data acquisition and analysis. Accordingly, we are optimistic that major insights will emerge from human connectomics in the coming decade. (C) 2012 Elsevier Inc. All rights reserved.
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