Causal influence of gamma oscillations on the sensorimotor rhythm

Gamma oscillations of the electromagnetic field of the brain are known to be involved in a variety of cognitive processes, and are believed to be fundamental for information processing within the brain. While gamma oscillations have been shown to be correlated with brain rhythms at different frequencies, to date no empirical evidence has been presented that supports a causal influence of gamma oscillations on other brain rhythms. In this work, we study the relation of gamma oscillations and the sensorimotor rhythm (SMR) in healthy human subjects using electroencephalography. We first demonstrate that modulation of the SMR, induced by motor imagery of either the left or right hand, is positively correlated with the power of frontal and occipital gamma oscillations, and negatively correlated with the power of centro-parietal gamma oscillations. We then demonstrate that the most simple causal structure, capable of explaining the observed correlation of gamma oscillations and the SMR, entails a causal influence of gamma oscillations on the SMR. This finding supports the fundamental role attributed to gamma oscillations for information processing within the brain, and is of particular importance for brain-computer interfaces (BCIs). As modulation of the SMR is typically used in BCIs to infer a subject's intention, our findings entail that gamma oscillations have a causal influence on a subject's capability to utilize a BCI for means of communication. (C) 2010 Elsevier Inc. All rights reserved.