期刊
NEUROIMAGE
卷 56, 期 1, 页码 102-113出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2011.01.054
关键词
Source localization; Distributed sources; EEG; MEG; MUSIC; Higher order statistics
资金
- Region Bretagne
We propose a new MUSIC-like method, called 2q-ExSo-MUSIC (q >= 1). This method is an extension of the 2q-MUSIC (q >= 1) approach for solving the EEG/MEG inverse problem, when spatially-extended neocortical sources (ExSo) are considered. It introduces a novel ExSo-MUSIC principle. The novelty is two-fold: i) the parameterization of the spatial source distribution that leads to an appropriate metric in the context of distributed brain sources and ii) the introduction of an original, efficient and low-cost way of optimizing this metric. In 2q-ExSo-MUSIC, the possible use of higher order statistics (q >= 2) offers a better robustness with respect to Gaussian noise of unknown spatial coherence and modeling errors. As a result we reduced the penalizing effects of both the background cerebral activity that can be seen as a Gaussian and spatially correlated noise, and the modeling errors induced by the non-exact resolution of the forward problem. Computer results on simulated EEG signals obtained with physiologically-relevant models of both the sources and the volume conductor show a highly increased performance of our 2q-ExSo-MUSIC method as compared to the classical 2q-MUSIC algorithms. (C) 2011 Elsevier Inc. All rights reserved.
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