4.7 Article Proceedings Paper

Continuous medial representation of brain structures using the biharmonic PDE

期刊

NEUROIMAGE
卷 45, 期 1, 页码 S99-S110

出版社

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2008.10.051

关键词

Medial representation; Skeletons; Deformable models; Computational anatomy; Shape analysis

资金

  1. NIA NIH HHS [K25 AG027785, K25 AG027785-02, AG027785] Funding Source: Medline
  2. NINDS NIH HHS [NS061111, R21 NS061111-02, R21 NS061111] Funding Source: Medline

向作者/读者索取更多资源

A new approach for constructing deformable continuous medial models for anatomical structures is presented. Medial models describe geometrical objects by first specifying the skeleton of the object and then deriving the boundary surface corresponding to the skeleton. However, an arbitrary specification of a skeleton will not be valid unless a certain set of sufficient conditions is satisfied. The most challenging of these is the non-linear equality constraint that must hold along the boundaries of the manifolds forming the skeleton. The main contribution of this paper is to leverage the biharmonic partial differential equation as a mapping from a codimension-0 subset of Euclidean space to the space of skeletons that satisfy the equality constraint. The PDE supports robust numerical solution on freeform triangular meshes, providing additional flexibility for shape modeling. The approach is evaluated by generating continuous medial models for a large dataset of hippocampus shapes. Generalizations to modeling more complex shapes and to representing branching skeletons are demonstrated. (C) 2008 Elsevier Inc. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据