期刊
NEUROIMAGE
卷 43, 期 3, 页码 447-457出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2008.07.009
关键词
Human; White matter; Atlas; Association fiber; Magnetic resonance imaging; Diffusion tensor
资金
- NCRR NIH HHS [P41 RR015241-060003, U24 RR021382-03, P41 RR015241-078615, U24 RR021382, P41 RR015241, P41 RR015241-050003, P41 RR015241-086350, P41 RR015241-040003, U24 RR021382-02, U24RR0213820, U24 RR021382-01] Funding Source: Medline
- NIA NIH HHS [R01 AG020012-05, R01 AG020012-07, R01 AG020012-02, R01 AG020012-03, R01 AG020012-04, R01 AG020012-01, R01 AG020012, R01AG20012, R01 AG020012-06A1] Funding Source: Medline
- NIBIB NIH HHS [P01 EB00195, P01 EB001955-14, P01 EB001955-13, P41 EB015909, P01 EB001955-11, P01 EB001955-15, P01 EB001955-12] Funding Source: Medline
Structural delineation and assignment are the fundamental steps in understanding the anatomy of the human brain. The white matter has been structurally defined in the past only at its core regions (deep white matter). However, the most peripheral white matter areas, which are interleaved between the cortex and the deep white matter, have lacked clear anatomical definitions and parcellations. We used axonal fiber alignment information from diffusion tensor imaging (DTI) to delineate the peripheral white matter, and investigated its relationship with the cortex and the deep white matter. Using DTI data from 81 healthy subjects, we identified nine common, blade-like anatomical regions, which were further parcellated into 21 subregions based on the cortical anatomy. Four short association fiber tracts connecting adjacent gyri (U-fibers) were also identified reproducibly among the healthy population. We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies. (C) 2008 Elsevier Inc. All rights reserved.
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