期刊
NEUROGASTROENTEROLOGY AND MOTILITY
卷 24, 期 4, 页码 -出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1365-2982.2011.01846.x
关键词
abdominal accommodation; abdominal distension; abdominal muscles; bloating; diaphragm; electromyography; intercostal muscles; intestinal gas; ultrasonography
资金
- Spanish Ministry of Education (Direccion General de Investigacion) [SAF 2009-07416]
- Fundacio La Marato TV3 [MARATV3_072010]
- Instituto de Salud Carlos III
- Freiwillige Akademische Gesellschaft (Basel, Switzerland)
- Gottfried und Julia Bangerter-Rhyner-Stiftung (Bern, Switzerland)
- Comision Nacional de Investigacion Cientifica y Tecnologica-Gobierno de Chile
- Pontificia Universidad Catolica de Chile
- Spanish Ministry of Health [ISC III 03/00051]
- SAF [2009-07416]
Background We previously showed that changes in intra-abdominal content induce a volume-dependent muscular response of the anterior abdominal wall and the diaphragm. We aimed to determine the contribution of the thorax to abdominal accommodation and the influence of the intra-abdominal expansion rate.Background We previously showed that changes in intra-abdominal content induce a volume-dependent muscular response of the anterior abdominal wall and the diaphragm. We aimed to determine the contribution of the thorax to abdominal accommodation and the influence of the intra-abdominal expansion rate. Methods Gas (1440 mL total load) was infused into the colon of nine healthy subjects, while abdominothoracic perimeters (by tape measure), electromyography (EMG) activity of the diaphragm (via six ring electrodes over an esophageal tube in the hiatus), intercostals and anterior abdominal wall (via five pairs of surface electrodes) and the position of the diaphragm by ultrasonography were measured. Infusion rates of 24, 48, and 96 mL min) 1 were tested on separate days. Key Results Gas infusion induced anterior abdominal wall contraction (18 +/- 1% EMG increment; P < 0.001) with relatively modest girth increment (4.9 +/- 0.9 mm; P = 0.001), diaphragmatic relaxation (by 15 +/- 1%; P < 0.001) with cephalad displacement (by 23 +/- 6 mm; P = 0.005), and intercostal contraction (by 19 +/- 2%; P < 0.001) with increased thoracic perimeter (by 2.0 +/- 0.5 mm; P = 0.009). Responses were similar with the three infusion rates. Conclusions & Inferences Accommodation of intra-abdominal loads involves a volume-related integrated abdomino-thoracic response regardless of the expansion rate.
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