期刊
NEUROEPIDEMIOLOGY
卷 36, 期 3, 页码 183-191出版社
KARGER
DOI: 10.1159/000327749
关键词
Cardiovascular comorbidities; Multiple sclerosis; Physical activity
资金
- National Institute of Neurological Diseases and Stroke [NS054050]
- National Multiple Sclerosis Society [RG 3926A2/1]
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R03NS054050] Funding Source: NIH RePORTER
Background: This study examined the possibility of a linear, inverse association between physical activity and the number of self-reported cardiovascular comorbidities in persons with multiple sclerosis (MS). Methods: The sample included 561 persons with MS who completed demographic, cardiovascular comorbidity, disability status, and physical activity self-report assessments, and then wore an accelerometer for 7 days. The data were analyzed using bivariate correlation and multiple linear regression analyses. Results: Bivariate correlation analysis indicated that there were statistically significant, inverse associations between the number of self-reported cardiovascular comorbidities and objectively measured (r = -0.192, p = 0.0001) and self-reported (r = -0.151, p = 0.0001) physical activity. The first multiple linear regression indicated that objectively measured physical activity was significantly associated with the number of self-reported cardiovascular comorbidities (B = -0.003, SE B = 0.001, beta = -0.128), even after controlling for confounding variables. The second multiple linear regression indicated that self-reported physical activity, too, was significantly associated with the number of self-reported cardiovascular comorbidities (B = -0.011, SE B = 0.004, beta = -0.114), even after controlling for confounding variables. Conclusion: Physical activity was associated with the number of self-reported cardiovascular comorbidities, independent of disability status and other possible confounding variables, in persons with MS. Copyright (C) 2011 S. Karger AG, Basel
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