期刊
NEUROEPIDEMIOLOGY
卷 34, 期 1, 页码 34-42出版社
KARGER
DOI: 10.1159/000255464
关键词
Dementia; Mild cognitive impairment; Telephone Interview for Cognitive Status-modified
资金
- National Institute on Aging [P50 AG016574, U01 AG006786]
- National Institute of Mental Health [K01 MH068351]
- National Institute of Aging [K01 AG028573]
- National Institute of Arthritis and Musculoskeletal and Skin Diseases [R01 AR030582]
- Robert H. and Clarice Smith and Abigail van Buren Alzheimer's Disease Research Program
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR030582] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [K01MH068351] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [U01AG006786, P50AG016574, K01AG028573] Funding Source: NIH RePORTER
Background: The telephone assessment of cognitive functions may reduce the cost and burden of epidemiological studies. Methods: We validated the Telephone Interview for Cognitive Status-modified (TICS-m) using an extensive in-person assessment as the standard for comparison. Clinical diagnoses of normal cognition, mild cognitive impairment (MCI), or dementia were established by consensus of physician, nurse, and neuropsychological assessments. Results: The extensive in-person assessment classified 83 persons with normal cognition, 42 persons with MCI, and 42 persons with dementia. There was considerable overlap in TICS-m scores among the three groups. Receiver operating characteristic curves identified <= 31 as the optimal cutoff score to separate subjects with MCI from subjects with normal cognition (sensitivity = 71.4%; subjects with dementia excluded), and <= 27 to separate subjects with dementia from subjects with MCI (sensitivity = 69.0%; subjects with normal cognition excluded). The TICS-m performed well when subjects with MCI were pooled either with subjects with dementia (sensitivity = 83.3%) or with subjects with normal cognition (sensitivity = 83.3%). Conclusions: Although the TICS-m performed well when using a dichotomous classification of cognitive status, it performed only fairly in separating MCI from either normal cognition or dementia. The TICS-m should not be used as a free-standing tool to identify subjects with MCI, and it should be used with caution as a tool to detect dementia. Copyright (C) 2009 S. Karger AG, Basel
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