期刊
NEUROCASE
卷 18, 期 6, 页码 441-449出版社
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/13554794.2011.627341
关键词
Cocaine; Functional connectivity; fMRI; Language; Noradrenergic
资金
- National Alliance for Autism Research [1033/DB//01/201/-005-00-00]
- NIDA [R21 DA015734]
- NINDS [K23 NS43222]
- OSU
- Wright Center for Innovation
- University of Missouri Department of Radiology
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [K23NS043222] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R21DA015734] Funding Source: NIH RePORTER
Recent research revealed decreased access to semantic and associative networks in acute cocaine withdrawal. In autism, such behavioral outcomes are associated with decreased functional connectivity using functional magnetic resonance imaging. Therefore, we wished to determine whether connectivity is also decreased in acute cocaine withdrawal. Eight subjects in acute cocaine withdrawal were compared to controls for connectivity in language areas while performing a task involving categorization of words according to semantic and phonological relatedness. Acute withdrawal subjects had significantly less overall connectivity during semantic relatedness, and a trend towards less connectivity during phonological relatedness. Of potential future interest is whether this might serve as an imaging marker for treatment in patients.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据