期刊
NEUROBIOLOGY OF LEARNING AND MEMORY
卷 96, 期 4, 页码 583-595出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.nlm.2011.02.016
关键词
Chronic stress; HPA axis; Glucocorticoids; Cognition; Mental health
资金
- Canadian Institutes of Health Research
- Canadian Institutes of Health Research, Institute of Gender and Health and Gender
This review aims to discuss the evidence supporting the link between chronic stress, cognitive function and mental health. Over the years, the associations between these concepts have been investigated in different populations. This review summarizes the findings that have emerged from older populations as well as from populations suffering from pathological aging, namely Mild Cognitive Impairment and Alzheimer's Disease. Although older adults are an interesting population to study in terms of chronic stress, other stress-related diseases can occur throughout the lifespan. The second section covers some of these stress-related diseases that have recently received a great deal of attention, namely burnout, depression, and post-traumatic stress disorder. Given that chronic stress contributes to the development of certain pathologies by accelerating and/or exacerbating pre-existing vulnerabilities that vary from one individual to the other, the final section summarizes data obtained on potential variables contributing to the association between chronic stress and cognition. (C) 2011 Elsevier Inc. All rights reserved.
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