期刊
NEURAL REGENERATION RESEARCH
卷 9, 期 7, 页码 766-772出版社
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/1673-5374.131589
关键词
nerve regeneration; magnetic resonance imaging; stroke; cerebral cortex; motor cortex; voxel-based lesion symptom mapping; motor function; prognosis; neural regeneration
资金
- University of South Carolina McCausland Center for Brain Imaging
Many studies have examined motor impairments using voxel-based lesion symptom mapping, but few are reported regarding the corresponding relationship between cerebral cortex injury and lower limb motor impairment analyzed using this technique. This study correlated neuronal injury in the cerebral cortex of 16 patients with chronic stroke based on a voxel-based lesion symptom mapping analysis. Neuronal injury in the corona radiata, caudate nucleus and putamen of patients with chronic stroke could predict walking speed. The behavioral measure scores were consistent with motor deficits expected after damage to the cortical motor system due to stroke. These findings suggest that voxel-based lesion symptom mapping may provide a more accurate prognosis of motor recovery from chronic stroke according to neuronal injury in cerebral motor cortex.
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