期刊
NEOTROPICAL ICHTHYOLOGY
卷 12, 期 1, 页码 153-164出版社
SOC BRASILEIRA ICTIOLOGIA
DOI: 10.1590/S1679-62252014000100017
关键词
Astyanax altiparanae; Biomonitoring; Biotransformation; Genotoxicity; Pesticides
类别
资金
- Brazilian research institutions CNPq (INCT-TA/CNPq) [573949/2008-5]
- Fundacao Araucaria
Aquatic ecosystems in areas with intense agricultural activity are subject to pesticide contamination, which may compromise the health of the fish. In order to verify the quality of the water and the possible effects of pesticides on fish, a method that combines different biomarker responses into an index named integrated biomarker response (IBR) was applied using the biological alterations in the Neotropical fish Astyanax altiparanae. Fish were maintained in situ at five sites along a stream that runs in an agricultural area and in a stream within a forest fragment, considered a reference site. After seven days of exposure the following alterations were observed in fish confined at experimental sites: increased activity of glutathione-S-transferase (GST) and catalase (CAT) and increase in the content of reduced glutathione (GSH) in liver and gills, reduction of acetylcholinesterase (AChE) activity in the brain and muscle, increase in the occurrence of DNA strand breaks and in the frequency of micronuclei (MN) and nuclear abnormalities (ENA) in erythrocytes. The IBR highlighted three sites as the most affected, as the animals confined at these sites showed greater variations in biological responses. The biomarkers most important for the IBR results were GST, AChE, DNA breaks and ENA.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据