期刊
NATURWISSENSCHAFTEN
卷 96, 期 1, 页码 129-133出版社
SPRINGER
DOI: 10.1007/s00114-008-0443-3
关键词
Radicals; Polyphenols; Lipid peroxidation; TBARS
资金
- University Grants Commission, New Delhi
- Institute of Himalayan Bioresource Technology (IHBT)
Polyphenols and polyphenol-rich fractions of plants have been reported to have protective effects against lipid peroxidation, most probably by serving as scavengers of free radicals and/or by chelating metal ions. In the present study, the effect of different extracts/subfractions of Chickrassy (Chukrasia tabularis) on peroxyl radical mediated damage to the polyunsaturated fatty acids was investigated. Liver homogenate was used as experimental material. The production of malondialdehyde served as a marker of lipid peroxidation and oxidative stress. It was observed that polyphenol-rich fractions, particularly the ethyl acetate fractions of bark and leaves, showed the highest protective activity of 83.02% and 88.62% inhibition, respectively. This study will help in knowing the scientific validation of this plant, for its use in ayurvedic formulations.
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