相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors
Lukasz Skora et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Explaining why Gleevec is a specific and potent inhibitor of Abl kinase
Yen-Lin Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
NMR line shapes and multi-state binding equilibria
Evgenii L. Kovrigin
JOURNAL OF BIOMOLECULAR NMR (2012)
The Different Flexibility of c-Src and c-Abl Kinases Regulates the Accessibility of a Druggable Inactive Conformation
Silvia Lovera et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
Georg E. Winter et al.
NATURE CHEMICAL BIOLOGY (2012)
Evolution of the eukaryotic protein kinases as dynamic molecular switches
Susan S. Taylor et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)
The Evolution of Protein Kinase Inhibitors from Antagonists to Agonists of Cellular Signaling
Arvin C. Dar et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)
Backbone assignment of the tyrosine kinase Src catalytic domain in complex with imatinib
Ramon Campos-Olivas et al.
BIOMOLECULAR NMR ASSIGNMENTS (2011)
Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms
Natalia Jura et al.
MOLECULAR CELL (2011)
Defining the conserved internal architecture of a protein kinase
Alexandr P. Kornev et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Molecular Dynamics Simulations Show That Conformational Selection Governs the Binding Preferences of Imatinib for Several Tyrosine Kinases
Alexey Aleksandrov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
FitSpace Explorer: An algorithm to evaluate multidimensional parameter space in fitting kinetic data
Kenneth A. Johnson et al.
ANALYTICAL BIOCHEMISTRY (2009)
Tyrosine-phosphorylation: thirty years and counting
Tony Hunter
CURRENT OPINION IN CELL BIOLOGY (2009)
A conserved protonation-dependent switch controls drug binding in the Abl kinase
Yibing Shan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Small Molecule Recognition of c-Src via the lmatinib-Binding Conformation
Arvin C. Dar et al.
CHEMISTRY & BIOLOGY (2008)
Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib
Navratna Vajpai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty
Markus A. Seeliger et al.
STRUCTURE (2007)
Thermofluor-based high-throughput stability optimization of proteins for structural studies
Ulrika B. Ericsson et al.
ANALYTICAL BIOCHEMISTRY (2006)
Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance
Mohammad Azam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A Src-like inactive conformation in the Abl tyrosine kinase domain
Nicholas M. Levinson et al.
PLOS BIOLOGY (2006)
NMR characterization of kinase p38 dynamics in free and ligand-bound forms
M Vogtherr et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
The CCPN data model for NMR spectroscopy: Development of a software pipeline
WF Vranken et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation
SW Cowan-Jacob et al.
STRUCTURE (2005)
Structural basis for the autoinhibition of c-Abl tyrosine kinase
B Nagar et al.
CELL (2003)
The conformational plasticity of protein kinases
M Huse et al.
CELL (2002)
Protein kinases - the major drug targets of the twenty-first century?
P Cohen
NATURE REVIEWS DRUG DISCOVERY (2002)
Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase
T Schindler et al.
SCIENCE (2000)