期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 20, 期 1, 页码 5-7出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2482
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资金
- NIGMS NIH HHS [R37 GM049650] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R37GM049650] Funding Source: NIH RePORTER
Chromatin-remodeling enzymes use the energy from ATP hydrolysis to mobilize, disrupt or change the histone composition of nucleosomes, facilitating nearly every nuclear event. Two recent studies indicate that remodeling enzymes harness the power of an ancient constitutively active DNA translocase and that different remodeling enzymes may use specialized coupling domains that communicate the presence of nucleosomal epitopes to regulate translocase and remodeling activity.
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